• noun:   an annoyance

  Example: "Those children are a damn plague"

• noun:   any large scale calamity (especially when thought to be sent by God)
• noun:   any epidemic disease with a high death rate
• noun:   a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of an infected rat flea (especially bubonic plague)
• noun:   a swarm of insects that attack plants

  Example: "A plague of grasshoppers"

• verb:   cause to suffer a blight
• verb:   annoy continually or chronically

Related words...