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Definitions of GPI:
  • noun:   (pathology) Initialism of general paresis of the insane. [(pathology) A neuropsychiatric disorder affecting the brain, caused by late-stage syphilis.]
  • noun:   (pathology) Initialism of general paralysis of the insane. [Synonym of general paresis of the insane]
  • noun:   (economics) Initialism of genuine progress indicator.

(Definitions from Wiktionary)

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