Definitions of Madonna:
- noun: United States pop singer and sex symbol during the 1980s (born in 1958)
- noun: the mother of Jesus; Christians refer to her as the Virgin Mary; she is especially honored by Roman Catholics
- name: A female given name (rare: 1 in 16666 females; popularity rank in the U.S.: #1176)
- name: A surname (very rare: popularity rank in the U.S.: #20720)