Definitions of prohibition:

• noun:   the action of prohibiting or inhibiting or forbidding (or an instance thereof)

  Example: "They were restrained by a prohibition in their charter"

• noun:   a law forbidding the sale of alcoholic beverages

  Example: "In 1920 the 18th amendment to the Constitution established prohibition in the US"

• noun:   a decree that prohibits something
• noun:   refusal to approve or assent to
• noun:   the period from 1920 to 1933 when the sale of alcoholic beverages was prohibited in the United States by a constitutional amendment